Quoted for emphasis.The saddest thing in Bg 2 for me is Viconia's epilogue. Even if it's something that could have happened any time, it hurts. You go through her tort... ehemm, romance to get that sad ending. Only for that I almost always install Edwin-ToB alternate Viconia's epilogue if I plan to romance her. It's way much better. I'm a good-endings addict.
Yoshimo's end is also very disgusting. Not only I like him a lot, he is very powerfull and his end is a real pain.
The most sad thing I did and always do is trying to install new romance mods for my male PC (female mods) to later not being capable of not romancing Jaheira, I'm so attached to her that it hurts me to:
-don't take her into the party (appart from her usefulness which for me is very high), I feel like betraying her. The same happens with Minsc and Imoen, I feel that they are my friends and have put their, possible without me peaceful lives, at danger for me that I'm not able to leave them or to get they chunked. I always reload if that happens.
-don't romance her and decide for another female. Yes, she can be annoying at times, but SHE IS JAHEIRA!!! She is lefting her organisation for you, fighting all kind of internal conflicts for you.
So you can see, I'm totally sick with this game. I will never be able to stop playing it. It's a drug.
Sad Vicky ending, both romanced and not.(The non made me believe that maybe she wasn't just a evil cruel harridan, and I managed to make myself play through with her, with my evil guy, but it didn't turn out too well. She just wasn't evil enough.
But the emphasis really goes on that last part with Jaheira. So, hear hear.