I really, really, really like the idea of taking over the Copper Coronet as a stronghold for all classes.
A good PC could gain Hendak as an
NPC and turn the CC into a nice place and work towards cleaning up the slums.
An evil PC could become the ultimate slumlord. Pimp, slaver, criminal mastermind and arms dealer all rolled into one nasty package. Protecting your whores from violent clients (or at least making them pay for damage), negotiating the sale of illegal magic, taking out select government officials, guarding slave caravans, the possibilities are endless. And if coupled with some of the class stronghold, even more possibilities are opened up. Obviously there's the thief stronghold, but how about the mage stronghold, the planar sphere. Suddenly there's evil cults based in the CC, secret demon-summoning rooms, expensive succubus hookers, etc. Maybe even making the slums so disgustingly degenerate and fiend-infested that the area, or even the city itself, is dragged into the Hells (now there's a great ending in the epilogue).