I don't mind high fantasy (tolkien-like world), but all games in the same corner of the world (sword coast), really made me frustrated.
I welcome Bioware's decision, it was a wise one. They are not encumbered with licenses and other crap that hinders development. Hopefully they hired talented people who are able to build a complete world from the grounds up.
Only Toril has enough space for another 10 RPG's. But I do wonder why Bioware set all his D&D games on the Sword Coast.
Personally, I don't have anything against a new setting, as a concept. But : in BG were more than 300 spells. DA will probably have a lot of spells too and when I think that I had to get used with them again, my enthuziasm crashes.